Why is Sex an Important Consideration in Toxicology?
Sex-based differences in toxicology are crucial as males and females may exhibit different responses to the same chemical exposure. Hormonal differences can influence metabolic pathways and immune responses, affecting toxicity. For instance, the presence of estrogen in females may alter the metabolism of certain drugs, leading to varying therapeutic and adverse effects compared to males. Recognizing these differences is important for accurate risk assessment and treatment.
