Why Is Surface Area to Volume Ratio Important in Toxicology?
The SA:V ratio is vital in toxicology for several reasons. First, it affects the rate of diffusion of substances into and out of cells. A higher ratio means that a cell or particle has more surface area available for diffusion relative to its volume. This can influence how quickly a toxin can enter a cell and begin exerting its effects. Conversely, a lower ratio might mean slower diffusion rates, potentially affecting the toxicokinetics of a substance.
