Why is the Central Nervous System a Target for Toxicants?
The CNS is a primary target for toxicants because of its complex structure and vital functions. It is particularly sensitive due to the high lipid content, which facilitates the accumulation of lipid-soluble toxicants. Furthermore, the blood-brain barrier can be bypassed by certain chemicals, allowing them to exert neurotoxic effects. Additionally, the CNS has limited regenerative capacity, making recovery from damage challenging.