Why is the G1 Phase Important in Toxicity Testing?
The G1 phase serves as an important checkpoint in toxicity testing because its disruption can indicate the potential of a substance to cause cellular damage or induce carcinogenesis. By studying how a compound affects the G1 phase, toxicologists can better understand its potential risks. Endpoint assays measuring cell viability, proliferation, and DNA damage are often used to assess the impact on the G1 phase.
