Are There Any Natural Compounds That Target Lipid II?
Yes, several natural compounds are known to target lipid II. Lantibiotics, such as nisin, are a class of peptide antibiotics that bind to lipid II. These naturally occurring compounds are produced by certain bacterial species as a defense mechanism against competitors. Nisin binds to lipid II, forming pores in the bacterial membrane and leading to cell lysis. The study of lantibiotics offers insights into the natural strategies for targeting lipid II and the potential for developing synthetic analogs.
