Are There Any Risks Associated with ASM Inhibitors?
While ASM inhibitors hold promise, there are potential risks that must be considered. Disruption in sphingolipid metabolism can affect cellular functions and might lead to unintended side effects. Long-term inhibition of ASM could potentially alter lipid homeostasis, and thus, careful dosing and monitoring are essential in therapeutic applications. Research is ongoing to better understand the safety profile of these inhibitors.