The primary function of Cremophor EL is to enhance the solubility of hydrophobic compounds, particularly in intravenous formulations. Many drugs have limited water solubility, which impedes their bioavailability and therapeutic efficacy. Cremophor EL can improve drug solubility, enabling effective dosing and treatment outcomes. It is widely used in formulations such as paclitaxel, an anti-cancer drug, and cyclosporine, an immunosuppressant.
