caspase activation

Can Caspase Inhibition Be Used Therapeutically?


Yes, inhibiting caspase activity has therapeutic potential in preventing unwanted cell death. In the context of toxicology, caspase inhibitors are explored as potential treatments to mitigate tissue damage caused by toxic agents. For example, caspase inhibitors are being studied for their ability to reduce liver damage in acetaminophen overdose. However, the challenge lies in selectively targeting pathological apoptosis without impairing normal apoptotic processes essential for cellular homeostasis.

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