Can CYP2E1 be Targeted for Therapeutic Intervention?
Targeting CYP2E1 for therapeutic intervention is an area of ongoing research. Inhibitors of CYP2E1 may offer a strategy to mitigate the toxic effects of certain drugs and chemicals by reducing their bioactivation. However, the challenge lies in achieving selectivity, as CYP2E1 shares substrates with other cytochrome P450 enzymes. Continued research into selective inhibitors and their clinical applications is needed.
