Can Genetic Predisposition and Toxins Interact in Neurodegenerative Disorders?
Yes, genetic predisposition can interact with environmental toxins to modulate the risk of developing neurodegenerative disorders. Individuals with specific genetic mutations may be more susceptible to the harmful effects of environmental toxins. For example, mutations in the LRRK2 gene have been shown to increase susceptibility to certain pesticides, which may contribute to the onset of Parkinson's disease. This gene-environment interaction underscores the importance of personalized approaches in understanding and preventing neurodegenerative diseases.