What Are the Mechanisms of Toxicity in Neurodegeneration?
The mechanisms by which environmental toxins induce neurodegeneration are diverse and complex. One common mechanism is the induction of oxidative stress, which can lead to cellular damage and death. Toxins can also interfere with apoptosis pathways, disrupt mitochondrial function, and alter protein aggregation processes. These disruptions can result in neuronal death and the progressive loss of neurological function seen in neurodegenerative disorders.