In some cases, loss of function can be reversible if the underlying cause is addressed. For instance, if a toxicant-induced loss of function is due to reversible binding, removing the toxicant may restore function. However, in cases where there is permanent damage, such as a mutational change leading to the loss of a critical protein, reversal may not be possible. Therapeutic strategies may involve using drugs to bypass the non-functional pathway or employing gene therapy techniques to correct the genetic defect.
