What are the Implications of Loss of Function in Toxicology?
The implications of loss of function in toxicology are significant. When a critical enzyme or receptor loses its function, it can disrupt metabolic pathways, impact signal transduction, and lead to cellular dysfunction. This can result in organ toxicity, developmental defects, or increased susceptibility to diseases. Understanding these implications helps in assessing the risk associated with exposure to toxic substances and designing effective interventions.