Can MAPK Pathway Inhibition Mitigate Toxic Effects?
Inhibition of the MAPK pathway can sometimes mitigate the harmful effects of toxins. For instance, blocking the JNK or p38 MAPK pathways can prevent apoptosis and reduce tissue damage in certain toxicological models. However, this approach must be carefully balanced, as MAPK signaling is also necessary for normal cellular processes and defense mechanisms.
