What are the Clinical Implications of Acetyl CoA Disruption?
Disruption of acetyl CoA metabolism can have significant clinical consequences. For instance, in mitochondrial toxicity, where the function of mitochondria is compromised, the production of acetyl CoA can be severely affected, leading to decreased ATP production and cellular dysfunction. This is particularly relevant in the context of drug-induced toxicity, where certain medications may impair mitochondrial function.