Can Toxicant-Induced Proteostasis Imbalance Be Mitigated?
Efforts to mitigate toxicant-induced proteostasis imbalance focus on enhancing the cell's natural protective mechanisms. This can involve the use of small molecules that act as chemical chaperones to stabilize protein folding or compounds that enhance autophagy, a process that helps clear damaged proteins. Additionally, antioxidants can be employed to reduce oxidative stress and its impact on protein integrity.