causal relationships

How are Causal Relationships Established?

To establish a causal relationship, toxicologists rely on a combination of epidemiological studies, laboratory experiments, and computational models. These methods help in understanding the dose-response relationship, which illustrates how different levels of exposure influence the severity of the effect.
Epidemiological Studies: These studies examine patterns, causes, and effects of health and disease conditions in defined populations and are crucial for establishing correlations that may indicate causation.
Laboratory Experiments: Animal models and in vitro studies provide controlled environments to observe direct effects and biological mechanisms at play.
Computational Models: These models simulate biological processes to predict possible outcomes and interactions, enhancing our understanding of potential risks.

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