Indoles undergo various metabolic processes in the body, primarily through the action of cytochrome P450 enzymes. These enzymes facilitate the conversion of indoles into hydroxylated metabolites, which are more water-soluble and can be excreted via urine. The metabolic pathways can vary based on the specific indole compound and the organism in question. For instance, indole-3-carbinol, found in cruciferous vegetables, is metabolized into diindolylmethane, which has been studied for its anticancer properties.
