Nanomaterials, due to their size and surface properties, may exhibit different toxicological profiles compared to their bulk counterparts. Evaluating these materials involves several approaches:
- In vitro studies: These are conducted using cell lines to observe cellular uptake, cytotoxicity, and genotoxicity. - In vivo studies: Animal models are used to study the biodistribution, metabolism, and potential toxic effects of nanomaterials. - Computational modeling: Helps predict the behavior and interactions of nanomaterials with biological systems.