Autophagy's role in cancer is complex, as it can have both tumor-promoting and tumor-suppressing effects. In cancer therapy, autophagy can influence the response to chemotherapeutic agents. Some cancer cells exploit autophagy for survival during treatment, making them more resistant to chemotherapy. On the other hand, inducing autophagic cell death can be a strategy to overcome drug resistance. Therefore, autophagy modulation is a promising approach in enhancing the efficacy of current cancer therapies.
