The evaluation of non-toxic materials involves rigorous testing and assessment. Scientists conduct toxicological studies to determine the safety levels of various substances. These studies may include acute, sub-chronic, and chronic toxicity tests, as well as assessments of carcinogenicity, reproductive toxicity, and ecotoxicity. Regulatory agencies, such as the Environmental Protection Agency (EPA) and the European Chemicals Agency (ECHA), establish guidelines and criteria for classifying materials as non-toxic.
