How Are Signal Transduction Pathways Involved in Toxicity?
Signal transduction pathways are involved in cellular responses to external signals, including toxins. These pathways can be activated or inhibited by toxic substances, leading to altered cellular function or cell death. For instance, disruptions in the MAPK pathway can result in uncontrolled cell proliferation or apoptosis. Toxins that mimic or block natural ligands can lead to inappropriate activation of pathways, contributing to toxic effects. Understanding these interactions is crucial for identifying potential therapeutic targets and developing interventions.
