How Can Disruption of the Mitotic Spindle Be Detected?
Disruption of the mitotic spindle can be detected using various techniques. Microscopy allows direct observation of spindle abnormalities, while assays measuring chromosomal aberrations and aneuploidy provide indirect evidence of spindle disruption. Advances in molecular biology have also led to the development of biomarkers for spindle damage, enabling more precise and early detection of toxic effects on cell division.
