How Can Gene Expression Patterns Predict Toxicity?
Gene expression patterns can serve as early indicators of toxicity, often before phenotypic changes are observable. By identifying specific gene signatures associated with toxicant exposure, researchers can predict the potential toxic effects of new chemicals. This approach is particularly useful in the field of predictive toxicology, where the goal is to assess the safety of compounds with limited empirical data. Furthermore, these patterns can provide insights into the mechanisms of action of toxicants, helping to identify potential therapeutic targets for mitigating adverse effects.
