How Can Glucose-6-Phosphatase Activity be Measured?
Glucose-6-phosphatase activity can be measured in laboratory settings using biochemical assays that quantify the conversion of glucose-6-phosphate to glucose. These assays are essential for diagnosing metabolic disorders such as GSD I and for evaluating the impact of toxic substances on liver function. Advanced techniques like mass spectrometry and Western blotting can also be used to assess the enzyme's activity and expression levels.