What are the Toxicological Implications of Glucose-6-Phosphatase Deficiency?
The deficiency of glucose-6-phosphatase can lead to the accumulation of glycogen and fat in the liver, resulting in liver enlargement and dysfunction. This can cause an increased risk of liver tumors, particularly hepatocellular carcinoma. Additionally, impaired glucose production can lead to severe hypoglycemia, posing a risk for neurological damage due to lack of energy supply to the brain.
