How Can Infections Alter the Pharmacokinetics of Toxins?
Infections can significantly alter the pharmacokinetics of toxins by affecting their absorption, distribution, metabolism, and excretion. Fever and inflammation can increase the permeability of blood vessels, affecting the distribution of toxins in the body. Additionally, infections can alter liver enzyme activity, which can modify the metabolism of toxins, either speeding up their clearance or leading to the accumulation of toxic metabolites.
