interfering substances

How Can Interfering Substances Be Identified?

Several strategies can be employed to identify interfering substances in toxicological analyses:
Sample pretreatment: Techniques such as filtration, centrifugation, or solid-phase extraction can be used to remove potential interferents before analysis.
Use of controls: Including positive and negative controls in assays can help identify unexpected interferences.
Spiking experiments: Adding known concentrations of potential interferents to samples can help assess their impact on the assay.
Advanced analytical techniques: Methods like mass spectrometry or chromatography can separate and identify interfering substances.

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