How Can Mechanistic Studies Aid in Risk Assessment?
Mechanistic studies provide valuable insights into dose-response relationships, thresholds for toxic effects, and interspecies variations in toxicity. By understanding the underlying mechanisms, toxicologists can develop more accurate models for risk assessment, which is crucial for setting exposure limits and safety standards. These studies also help identify biomarkers of exposure and effect, which can be used for monitoring and evaluating the impact of toxicants on human health and the environment.