Selective COX-2 inhibitors are a class of drugs designed to selectively block the cyclooxygenase-2 enzyme, which plays a key role in the inflammatory process. Unlike traditional non-steroidal anti-inflammatory drugs (NSAIDs) that inhibit both COX-1 and COX-2 enzymes, COX-2 inhibitors specifically target the COX-2 enzyme, aiming to reduce gastrointestinal toxicity associated with COX-1 inhibition.
