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mitochondrial function
How Can Mitochondrial Dysfunction Be Detected?
Several assays and techniques are used to assess mitochondrial function:
-
Oxygen Consumption Rate (OCR)
: Measures cellular respiration and ETC activity.
-
ATP Measurement
: Quantifies cellular ATP levels to assess mitochondrial bioenergetics.
-
Mitochondrial Membrane Potential Assays
: Uses dyes like JC-1 to evaluate the integrity of the mitochondrial membrane potential.
-
ROS Detection
: Utilizes fluorescent probes to measure intracellular ROS levels.
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