atp binding cassette (abc) transporters

How Do ABC Transporters Impact Pharmacokinetics and Pharmacodynamics?


ABC transporters significantly influence pharmacokinetics and pharmacodynamics by affecting drug absorption, distribution, and elimination. They can alter the bioavailability and clearance rates of medications, impacting their therapeutic window and dosing regimens. Understanding the transporter's role in drug handling is crucial for optimizing drug dosing and minimizing adverse effects.

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