Are There Any Strategies to Overcome ABC Transporter-Mediated Drug Resistance?
Several strategies have been proposed to overcome ABC transporter-mediated drug resistance, particularly in cancer therapy. These include the use of inhibitors that block the transporter function, the development of drugs that are not substrates for these transporters, and combination therapies that can bypass resistance mechanisms. Research is ongoing to identify safe and effective ways to circumvent the challenges posed by ABC transporters.
