How Do Additive Effects Differ from Synergistic and Antagonistic Effects?
In toxicology, it is essential to distinguish between additive, synergistic, and antagonistic effects. While additive effects result in a combined impact equal to the sum of individual effects, synergistic effects produce a combined impact greater than the sum. Conversely, antagonistic effects result in a combined impact less than the sum, as one chemical reduces the effect of another.