How do bile acid sequestrants compare to other lipid-lowering agents?
Compared to statins, which reduce cholesterol synthesis in the liver, bile acid sequestrants lower cholesterol by increasing its conversion to bile acids. While statins are generally more effective in reducing LDL cholesterol, bile acid sequestrants provide an alternative for those who cannot tolerate statins. Moreover, they can be used in combination with other lipid-lowering agents to achieve additive effects.
