What role do bile acid sequestrants play in toxicology?
In toxicology, bile acid sequestrants can be used to manage certain types of poisoning. By interrupting the enterohepatic circulation, these agents can enhance the elimination of toxins that undergo similar recycling. For instance, they may be employed to treat overdoses of drugs that are extensively metabolized and excreted into the bile, such as certain lipophilic substances. Additionally, they may help in reducing the systemic absorption of toxic compounds that are subject to biliary excretion.
