These interactions can manifest in various ways, including:
Gene-Modification: Environmental factors can alter gene expression through epigenetic modifications, such as DNA methylation and histone modification. Genetic Variants: Certain genetic variants can increase or decrease susceptibility to environmental toxins. For instance, polymorphisms in genes encoding metabolic enzymes can influence the metabolism of and response to chemicals. Protective Genes: Some genes may offer protection against environmental insults, potentially reducing the risk of toxic effects.