How Do Inflammasomes Relate to Toxicological Responses?
Inflammasomes are activated by a wide range of toxicants, including nanoparticles, heavy metals, and various environmental pollutants. When these substances are detected by the body, inflammasomes trigger a cascade of inflammatory responses. This can lead to tissue damage and contribute to the pathology of diseases such as asthma, cancer, and neurodegenerative disorders. In toxicological research, analyzing the inflammasome pathway helps in understanding how toxins cause cellular damage and the potential long-term health effects.
