What Challenges Exist in Inflammasome Research within Toxicology?
One of the main challenges is the complexity of inflammasome signaling pathways and their regulation. The activation of inflammasomes is influenced by various factors, including genetic predispositions and environmental conditions. This complexity makes it difficult to predict and control inflammasome responses accurately. Additionally, the redundancy and overlap among different inflammasomes pose challenges in pinpointing specific pathways involved in the response to toxicants.
