NSAIDs work by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins, substances that mediate inflammation and pain. In toxicology, NSAIDs can be used to alleviate pain and inflammation caused by exposure to certain toxins. However, they must be used cautiously, as they can cause gastrointestinal bleeding, renal impairment, and other adverse effects, particularly in patients with compromised health due to toxic exposure.