How do thioethers interact with biological systems?
Thioethers can interact with biological systems through various mechanisms. Their lipophilic nature allows them to easily penetrate cell membranes, potentially leading to adverse effects. Thioethers can be metabolized in the body through oxidation, primarily by cytochrome P450 enzymes, to form sulfoxides and sulfones, which may possess different toxicological properties compared to the parent compound. These metabolites can further react with cellular macromolecules, potentially causing cellular damage or triggering immune responses.
