respiratory alkalosis

How Do Toxic Agents Induce Respiratory Alkalosis?

Several toxic agents can induce respiratory alkalosis by stimulating the respiratory center in the brain, leading to hyperventilation. Some common substances include:
- Salicylates: Overdose of salicylates, such as aspirin, initially causes hyperventilation and respiratory alkalosis before leading to metabolic acidosis.
- Catecholamines: Elevated levels due to exogenous administration or endogenous release in response to stress can stimulate respiration.
- Theophylline: Overdose can lead to central nervous system stimulation and increased respiratory rate.
- Carbon monoxide: Although primarily causing hypoxia, it can also lead to hyperventilation as a compensatory mechanism.

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