hemorrhage

How Do Toxic Substances Cause Hemorrhage?

Certain toxins interfere with the physiological mechanisms that regulate blood clotting. For example, anticoagulant rodenticides, such as warfarin and brodifacoum, inhibit the synthesis of vitamin K-dependent clotting factors. Without these factors, the blood cannot clot properly, leading to excessive bleeding. Other substances, like snake venoms, contain enzymes and proteins that directly degrade blood components or interfere with platelet function, resulting in hemorrhage.

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