Toxicants can interfere with the cytoskeleton by binding to its components, thereby altering their functionality. For instance, colchicine binds to tubulin, preventing microtubule polymerization. This disruption can lead to impaired cell division and cell death. Similarly, phalloidin, a toxin from the Amanita mushroom, stabilizes actin filaments, hindering their normal dynamics and affecting cell motility and morphology.
