What role does the cytoskeleton play in drug delivery and resistance?
The cytoskeleton is pivotal in mediating drug delivery and resistance. It facilitates the transport of therapeutic agents within cells. However, alterations in cytoskeletal dynamics can lead to drug resistance, as seen in cancer cells where changes in actin filament organization affect the uptake and efficacy of chemotherapeutic agents. Understanding these processes can help in designing drugs that can bypass these barriers.
