Toxicants can disrupt tissue homeostasis by interfering with cellular processes. They may induce oxidative stress, DNA damage, or inflammation, leading to impaired cell function and death. For instance, exposure to certain heavy metals or chemicals can result in the excessive production of reactive oxygen species (ROS), which can damage cellular components and lead to apoptosis or necrosis. This disruption can impair the tissue's ability to repair itself and maintain its normal function.
