Once inside, toxicants are distributed throughout the body via the bloodstream. Distribution depends on several factors, including:
Blood Flow: Organs with higher blood flow, such as the liver, kidneys, and brain, may receive greater exposure. Lipid Solubility: Lipophilic toxicants tend to accumulate in fatty tissues, potentially causing prolonged effects. Binding to Proteins: Toxicants may bind to plasma proteins, affecting their transport and availability for interaction with target sites.
