Toxicokinetics is the study of how a chemical substance enters and moves through the body. It involves four main processes: absorption, distribution, metabolism, and excretion (ADME). Each of these processes can affect the internal dose:
Absorption: Determines how much of a substance enters the bloodstream. Distribution: Involves the dissemination of the chemical to various tissues and organs. Metabolism: The chemical is transformed into metabolites, which can be more or less toxic than the parent compound. Excretion: The process of eliminating the chemical from the body, typically through urine or feces.
