Several factors can influence the internal dose of a chemical. These include:
Route of Exposure: The way a chemical enters the bodyâwhether through inhalation, ingestion, or dermal contactâcan affect its absorption and distribution. Metabolism: Individual metabolic rates can vary, influencing how quickly a substance is broken down and eliminated. Age and Health Status: Young children, the elderly, and individuals with certain health conditions may absorb and process chemicals differently. Duration and Frequency of Exposure: Prolonged or repeated exposure can lead to higher internal doses.