How Do Toxins Affect Inhibitory Neurotransmitter Systems?
Toxins can affect inhibitory neurotransmitter systems in several ways. Some toxins, such as strychnine, act as antagonists at the glycine receptor, preventing glycine from binding and inhibiting its function. This disruption can lead to muscle spasms and convulsions. Other toxins, such as alcohol, can enhance the effects of GABA by increasing its binding affinity to the GABA receptor, leading to sedative effects. Studying these interactions is crucial for understanding the neurotoxic effects of different substances.
